Papillary cystadenoma of the epididymis

Last revised by Yuranga Weerakkody on 22 Dec 2020

Papillary cystadenomas of the epididymis are the second most common benign tumors of the epididymis after adenomatoid tumors and are common in patients with von Hippel-Lindau disease (vHL).

Papillary cystadenomas are usually asymptomatic.

They are more common in young men (20-40 years) 2. Approximately 30% of patients have vHL and ~35% (range 10-60%) of patients with vHL have papillary cystadenoma(s) 1,2.

Lesions are usually arising from the head of the epididymis and can present as a cystic lesion with a thick wall and several peripheral solid nodules with increased vascularity, partially or completely cystic or solid lesion and measuring up to 3 cm in diameter 1.

Considerations include:

Patients with bilateral papillary cystadenomas of the epididymis should be considered for vHL screening 2.

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