Pathogenesis is thought to be a cascade of processes from insufficient mucociliary clearance leading to sinus colonisation and chronic inflammatory response. The patient may only have a mild symptom or be asymptomatic.
Commonly only a single sinus is affected with the predilection for the maxillary sinus followed by the sphenoid sinus. The frontal and ethmoid are less often affected. A clue to the diagnosis includes soft tissue density within the sinus with/without foci of calcific deposit. Postobstructive change may be observed if the mycetoma obstructs the sinus drainage pathway leading to partial or complete sinus opacification 2.
Evidence of chronic inflammation with sclerosis and thickening of the wall of the paranasal sinuses. Careful evaluation of the sinus cavity is prudent to exclude bone erosion that is not a feature of mycetoma / chronic fungal sinusitis rather a feature of acute invasive fungal sinusitis 2.
MRI signal characteristics of mycetomas reflect the internal content of the mycelia, vegetative part of a fungus consisting of a conglomerate of hyphae. This contains primarily carbohydrates with some glycoproteins, macromolecular proteins, and iron and manganese.
- T1: low signal
- T2: low signal. The presences of paramagnetic elements further shorten the relaxation times, and this can be a highlight on the susceptibility weighted sequence 5
- T1 C+ (Gd): chronic inflammatory change of the sinus mucosa may enhance
- allergic fungal sinusitis
chronic invasive fungal sinusitis
- bone erosion
- soft tissue invasion
- immunocompromised patients
- paranasal sinus mucocoele
- sinonasal inverted papilloma
- inflammatory and infective conditions
- granulomatosis with polyangiitis (Wegener granulomatosis)
- paranasal sinus mucocoele
- silent sinus syndrome
- masses and neoplasms
- fibrous-osseous lesions
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