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Parathyroid hyperplasia is the diffuse enlargement of the parathyroid glands and is a less common cause of primary hyperparathyroidism.
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There is a female predilection (M:F = 1:3).
Most commonly an incidental finding of hypercalcemia in asymptomatic patients.
In ~50% of cases, there is asymmetric enlargement of the parathyroid glands.
- primary parathyroid hyperplasia
- secondary parathyroid hyperplasia
- renal failure
Nuclear medicine (Tc-99m MIBI) is the current modality of choice. 4DCT has been shown to be specific but not sensitive.
- double parathyroid adenoma
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