Pathological fracture risk (Harrington criteria)
Last revised by Dr Daniel J Bell ◉ on 05 Aug 2019
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Citation:
Knipe, H., Bell, D. Pathological fracture risk (Harrington criteria). Reference article, Radiopaedia.org. (accessed on 12 Aug 2022) https://doi.org/10.53347/rID-40746
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rID:
40746
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Synonyms:
- Harrington's criteria
- Pathological fracture risk: Harrington's criteria
- Harrington's criteria of pathological fracture risk
Harrington criteria can be used to predict which long bone skeletal metastases are at high risk of pathological fracture and should undergo prophylactic internal fixation. It preceded the Mirels classification for impending pathological fracture but has not been validated and its use is debated.
Classification
- >50% cortical bone destruction
- lesion >2.5 cm in size
- pathological avulsion fracture of the lesser trochanter
- functional pain after radiation therapy
References
- 1. Piccioli A, Spinelli MS, Maccauro G. Impending fracture: A difficult diagnosis. (2014) Injury. 45 Suppl 6: S138-41. doi:10.1016/j.injury.2014.10.038 - Pubmed
- 2. Browner BD, Jupiter JB, Krettek C et-al. Skeletal Trauma: Expert Consult (Browner, Skeletal Trauma). Saunders. ISBN:B00QT83ORI. Read it at Google Books - Find it at Amazon
- 3. Intramedullary Nailing: A Comprehensive Guide. Springer. ISBN:B00S5XKUGI. Read it at Google Books - Find it at Amazon
Related articles: Bone tumours
The differential diagnosis for bone tumors is dependent on the age of the patient, with a very different set of differentials for the pediatric patient.
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skeletal metastases
- morphology
- location
- impending fracture risk
- staging
- approach
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