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Citation:
Weerakkody Y, Bell D, Pembrolizumab induced pneumonitis. Reference article, Radiopaedia.org (Accessed on 20 Mar 2023) https://doi.org/10.53347/rID-93800
Pembrolizumab induced pneumonitis is a form of drug-induced lung disease occurring as a result of a response to the use of the programmed cell death protein 1 (PD1) inhibitor pembrolizumab. It may have variable pattern 2.
Pembrolizumab is also reported to have a high risk of inducing lung injury in patients with pre-existing interstitial lung disease 3.
See also
- 1. Fujita T, Hayama N, Kuroki T et al. Pembrolizumab-Induced Interstitial Lung Disease Following Thoracic Surgery in a Patient with Non-Small Cell Lung Cancer. Thorac Cancer. 2019;10(11):2179-82. doi:10.1111/1759-7714.13194 - Pubmed
- 2. Ueno R, Nemoto M, Uegami W, Fukuoka J, Misawa M. Pembrolizumab-Induced Pneumonitis with a Perilymphatic Nodular Pattern in a Lung Cancer Patient: A Radio-Pathologic Correlation. Respiratory Medicine Case Reports. 2019;26:168-70. doi:10.1016/j.rmcr.2019.01.001 - Pubmed
- 3. Fujita T, Kuroki T, Hayama N et al. Pembrolizumab for Previously Untreated Patients with Advanced Non-Small-Cell Lung Cancer and Preexisting Interstitial Lung Disease. Intern Med. 2020;59(16):1939-45. doi:10.2169/internalmedicine.4552-20 - Pubmed
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