Pepper syndrome

Last revised by Dr Candace Makeda Moore on 04 Dec 2020

Pepper syndrome is a term not readily used in day-to-day practice and usually refers to primary adrenal neuroblastoma with extensive liver metastases 1. In essence, it refers to stage 4S neuroblastoma (see staging of neuroblastoma).  Cohen syndrome, a genetic disorder, is sometimes referred to as Pepper syndrome as well but is not related.

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