Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Niknejad M, Bell D, Periapical granuloma. Reference article, Radiopaedia.org (Accessed on 13 Mar 2025) https://radiopaedia.org/articles/78496
Periapical granuloma (plural: granulomas or granulomata) refers to a localized mass-like region of chronic granulation tissue in relation to teeth formed in response to infection. It often results in relation to chronic apical periodontitis.
Terminology
The name of this condition is a misnomer as they are not true granulomas: no granulomatous inflammation is found.
Pathology
They contain granulation tissues, cell infiltrates and a fibrous capsule.
Radiographic features
CT
Periapical granulomas may have higher attenuation values than periapical cysts.
See also
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1. Meir H. Scheinfeld, Keivan Shifteh, Laura L. Avery, Harry Dym, R. Joshua Dym. Teeth: What Radiologists Should Know. (2012) RadioGraphics. 32 (7): 1927-44. doi:10.1148/rg.327125717 - Pubmed
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2. Lizio G et.al . Differential Diagnosis Between a Granuloma and Radicular Cyst: Effectiveness of Magnetic Resonance Imaging. (2018) International endodontic journal. doi:10.1111/iej.12933 - Pubmed
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3. Juerchott A, Pfefferle T, Flechtenmacher C, Mente J, Bendszus M, Heiland S, Hilgenfeld T. Differentiation of periapical granulomas and cysts by using dental MRI: a pilot study. (2018) International journal of oral science. 10 (2): 17. doi:10.1038/s41368-018-0017-y - Pubmed
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4. Zain R, Zain RN, Zain IK, Zain. Radiographic Features of Periapical Cysts and Granulomas. (1989) Singapore dental journal. doi: - Pubmed
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