Pericardial lipoma

Last revised by Daniel J Bell on 17 Mar 2024

Pericardial lipomas are slowly growing benign tumours of the pericardium that are asymptomatic unless large in size, where they can cause pressure symptoms.

Pericardial lipomas are usually asymptomatic.
Occasionally non-specific symptoms are present including:

  • chest pain

  • breathlessness

  • dizziness

  • syncope

Symptoms occur due to extrinsic compression of the heart, usually of the right atrium or ventricle, or compression of coronary artery or dysfunction of one of the heart valves 2.

True lipomas of the heart are encapsulated or enveloped by cardiac muscle. They may occur in any part of the heart including the pericardium 3.

The lipoma tends to be an echogenic structure adjacent to or inside the pericardium.

Seen as a fatty attenuating tumour that displays <0 HU density. No enhancement post-contrast administration. The lesion may not be well-circumscribed like other lipomas.

Exhibits bright signal on T1 and T2 with no contrast enhancement. Fat suppression techniques e.g. STIR, SPAIR, and fat saturation, confirm the fatty contents.

Imaging differential considerations include

As a broader differential consider

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