Pericardial mesothelioma refers to a mesothelioma arising primarily from the pericardium.
They are rare and are only thought to account for ~ 0.7% of all malignant mesotheliomas. There is male to female predominance of approximately 3:1.
The presentation of pericardial mesothelioma is nonspecific with complains of dyspnea, chest pain and weight loss.
Pericardial mesothelioma can present as a localized or as a diffuse mass.
Some reports suggest an association with asbestos exposure but being not as strong as for pleural mesothelioma. Others state no association with asbestos exposure.
- constrictive pericarditis
- pericardial effusion and cardiac tamponade
- heart failure
It is a lethal disease carrying a very poor prognosis. Surgical resection can be option for symptomatic relief.
- 1. Thomason R, Schlegel W, Lucca M et-al. Primary malignant mesothelioma of the pericardium. Case report and literature review. Tex Heart Inst J. 1994;21 (2): 170-4. Free text at pubmed - Pubmed citation
- 2. Santos C, Montesinos J, CastañEr E et-al. Primary pericardial mesothelioma. Lung Cancer. 2008;60 (2): 291-3. doi:10.1016/j.lungcan.2007.08.029 - Pubmed citation
- 3. Vigneswaran WT, Stefanacci PR. Pericardial mesothelioma. Curr Treat Options Oncol. 2002;1 (4): 299-302. Pubmed citation
- 4. Yilling F, Schlant R, Hertzler G et-al. Pericardial mesothelioma. Chest. 01;81 (4): 520-523. doi:10.1378/chest.81.4.520
- 5. Suman S, Schofield P, Large S. Primary pericardial mesothelioma presenting as pericardial constriction: a case report. Heart. 2004;90 (1): e4. Free text at pubmed - Pubmed citation