Pericardial mesothelioma

Pericardial mesothelioma refers to a mesothelioma arising primarily from the pericardium. 

Epidemiology

They are rare and are only thought to account for ~ 0.7% of all malignant mesotheliomas. There is male to female predominance of 2-4 : 1.2.

Pathology

Gross pathology

Pericardial mesothelioma can present as a localized or as a diffuse mass.

Associations

Some reports suggest an association with asbestos exposure but being not as strong as for pleural mesothelioma. Others state no association with asbestos exposure.

Clinical presentation

The presentation of pericardial mesothelioma is nonspecific with complains of dyspnea, chest pain and weight loss.  

Complications

• constrictive pericarditis
• pericardial effusion and cardiac tamponade
• heart failure

Prognosis

It is a lethal disease carrying a very poor prognosis. Surgical resection can be option for symptomatic relief.

See also

• primary cardiac tumours