Peripheral T cell lymphoma
Citation, DOI & article data
The word "peripheral" does not mean involvement in the extremities but refers to tumor cells that arise from lymphoid tissue outside of the bone marrow.
This lymphoma type develops from mature-stage T-cells and natural killer (NK) cells.
Peripheral T cell lymphoma can involve various organs including the sinonasal cavity, airway, intestinal tract, skin, lymph nodes, liver, lung, and musculoskeletal system.
Treatment and prognosis
Peripheral T cell lymphoma is generally considered to have a poorer outcome 3. Initially, combination therapy regimens are usually offered. Agents such as pralatrexate are used for refractory cases.
- 1. Lee H, Im J, Goo J et al. Peripheral T-Cell Lymphoma: Spectrum of Imaging Findings with Clinical and Pathologic Features. Radiographics. 2003;23(1):7-26; discussion 26-8. doi:10.1148/rg.231025018 - Pubmed
- 2. Choi J, Kim S, Kim E, Heran M. Peripheral T-Cell Lymphoma in the Neck: CT Findings of Lymph Node Involvement. AJNR Am J Neuroradiol. 2006;27(5):1079-82. PMC7975757 - Pubmed
- 3. Yang W, Jiang S, Lin J, Li Y. CT Findings Predict Survival of Patients with Peripheral T Cell Lymphoma: A Preliminary Study. Radiol Oncol. 2019;53(1):31-8. doi:10.2478/raon-2019-0005 - Pubmed