Citation, DOI, disclosures and article data
Citation:
Sarangi P, Gaillard F, Bickle I, Periwinkle sign (supratentorial ependymoma). Reference article, Radiopaedia.org (Accessed on 07 Oct 2024) https://doi.org/10.53347/rID-71637
Disclosures:
At the time the article was last revised Frank Gaillard had the following disclosures:
- Radiopaedia Australia Pty Ltd, Founder and CEO (ongoing)
- Biogen Australia Pty Ltd, Investigator-Initiated Research Grant for CAD software development in multiple sclerosis (past)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Frank Gaillard's current disclosures
The periwinkle sign has been coined to describe what has been claimed to be a characteristic appearance of intraparenchymal supratentorial ependymomas on non-enhanced CT axial images.
The central solid component sometimes demonstrates centripetal calcification surrounding the central necrotic core. This appearance is reminiscent of a periwinkle flower. More fanciful still, the often present surrounding peripheral cyst has been likened to a leaf 1.
Etymology
For reasons that are not immediately apparent a particular flower, the periwinkle, also known as myrtle herb (Vinca minor) is chosen, although in fairness many flowers would appear similar.
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1. Sandhya Mangalore, Saritha Aryan, Chandrajit Prasad, Vani Santosh. Imaging characteristics of supratentorial ependymomas: Study on a large single institutional cohort with histopathological correlation. (2015) Asian Journal of Neurosurgery. 10 (4): 276. doi:10.4103/1793-5482.162702 - Pubmed
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