Permeative process in bone

A true permeative process of bone, or moth-eaten appearance in bone, describes multiple small endosteal lucent lesions or holes, often with poorly defined margins, with sparing of the cortex. It is a bone marrow process.

The term 'moth-eaten' describes the pattern of destruction observed in fabric that has been eaten by moth larvae.  

The most common pathologies that may manifest with a permeative appearance include 1:

Mnemonic: FIRE MD

See also

Article information

rID: 21097
Tag: refs
Synonyms or Alternate Spellings:
  • Moth-eaten appearance in bone

Support Radiopaedia and see fewer ads

Cases and figures

  • Case 1: Ewing sarcoma
    Drag here to reorder.
  • Case 2: Burkitt lymphoma
    Drag here to reorder.
  • Updating… Please wait.

     Unable to process the form. Check for errors and try again.

     Thank you for updating your details.