Persistent right umbilical vein

A persistent right umbilical vein (PRUV) is an uncommon vascular anomaly which is often detected in utero.

The estimated prevalence is at ~2 per 1000 births 1-2.

In the normal situation the right umbilical vein begins to obliterate in the ~4th week of gestation and disappears by the 7th week. With a PRUV, the right umbilical vein remains open and the left umbilical vein usually obliterates. A PRUV may be also be supernumerary 6.


A PRUV can be intra or extra-hepatic. The former is much more commoner.


Numerous associated have been described (albeit as relatively low rates 3,9). They are commoner with the extra-hepatic type and include:

Antenatal ultrasound

It is usually detected in the 2nd to 3rd trimester. Assessment is usually made in the axial plane and colour Doppler is often required. An intra-hepatic persistent right umbilical vein may be seen as a umbilical vein abnormally connected to the right portal vein and the fetal gallbladder is positioned medial to the PRUV. 

When additional anomalies are ruled out, a PRUV in isolation carries a generally favourable outcome 1,9.

If a persistent right umbilical vein is detected, a careful sonographic anatomical survey is generally recommended to rule out more serious congenital malformations 10.

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Article information

rID: 13564
Sections: Anatomy, Pathology
Synonyms or Alternate Spellings:
  • Persistent right umbilical vein (PRUV)
  • PRUV
  • Persistence of the right umbilical vein
  • Right umbilical vein persistence

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