Persistent sciatic vein

Last revised by Mohammadtaghi Niknejad on 30 Jan 2023

Persistent sciatic vein is one of two known embryonic veins in the lower limb which may persist, the other being the lateral marginal vein. Although both are associated with Klippel-Trenaunay syndrome 1-3, only the lateral marginal vein is also referred to as the Klippel-Trenaunay vein.

The sciatic (or axial) vein is an embryonic lower limb vein that drains the lower thigh to the internal iliac, and usually regresses before birth 4. The persistent sciatic vein follows the course of the sciatic nerve in the posterior lower limb, and drains the lower thigh into the common iliac vein 5. It may have no valves, predisposing to chronic venous insufficiency.

Related pathology

Persistent sciatic vein has been associated with the following conditions:

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