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Phase 0 clinical trials

Last revised by Dr Henry Knipe on 17 Apr 2015

Phase 0 clinical trials are the first step in evaluating a possible new drug on humans, and are designed to evaluate the  pharmacodynamics and pharmacokinetics of the drug in humans. They are typically performed on a small number of subjects (e.g. a dozen or so) who are administered subtherapeutic doses 1

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