Phase 0 clinical trials
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At the time the article was created Frank Gaillard had no recorded disclosures.View Frank Gaillard's current disclosures
At the time the article was last revised Henry Knipe had no recorded disclosures.View Henry Knipe's current disclosures
Phase 0 clinical trials are the first step in evaluating a possible new drug on humans, and are designed to evaluate the pharmacodynamics and pharmacokinetics of the drug in humans. They are typically performed on a small number of subjects (e.g. a dozen or so) who are administered subtherapeutic doses 1.