Picture frame vertebral body

Picture frame vertebral body is a radiologic appearance in which the cortex of the vertebral body is thickened. This sign is seen in a patient with Paget disease

This is a result of disorganized new cortical bone formation after excessive osteoclastic activity causes the resorption of normal bone.

Radiographic features

At radiography, this results in increased opacity of the cortex on all sides of the vertebral body.

Differential diagnosis

  • rugger jersey spine
    • the characteristic sclerosis of the rugger jersey spine is seen only at the superior and inferior endplates
Share article

Article information

rID: 21487
Section: Signs
Tags: refs, cases
Synonyms or Alternate Spellings:
  • Picture frame vertebra
  • Picture frame sign

Support Radiopaedia and see fewer ads

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.