Pilonidal sinus

Pilonidal sinuses result from a skin and subcutaneous tissue infection, typically occurring at or near the upper part of the natal cleft of the buttocks. As such is it often also termed an intergluteal pilonidal sinus. While it can also occur at other sites (see location section), this article is focused on inter-gluteal pilonidal sinuses.

While it can potentially occur at any age, it is much less common in children and older individuals (e.g. those older than 45). The peak age of presentation is patients in their twenties. There is an increased male predilection.

It is characterised by natal cleft suppuration and is thought to initially result from a hair follicle infection. This can then lead to the subsequent formation of a subcutaneous abscess from a persistent folliculitis. Hair can then enter the abscess cavity and provoke a foreign body tissue reaction.

While it classically occurs in the intergluteal region, it can rarely occur at other sites (e.g. interdigital pilonidal sinus 4-5).

May show sinus anatomy to a reasonable degree in superficial cases.

Allows visualisation of tract anatomy also useful in assessment associated inflammation.

It is thought to have been initially described by Herbert Mayo in 1833 2.

Intergluteal pilonidal sinuses can be clinically difficult to differentiate from a fistula in ano.

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Article information

rID: 37670
Section: Pathology
Synonyms or Alternate Spellings:
  • Pilonidal sinus disease
  • Intergluteal pilonidal disease
  • Intergluteal pilonidal sinus
  • Pilonidal sinuses

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