Pineal germinoma

Pineal germinomas are the most common tumour of the pineal region accounting for ~50% of all tumours, and the majority (~80%) of intracranial germ cell tumours

There is a marked male predominance with a M:F of ~13:1. Most patients are 20 years or younger at the time of diagnosis. 

They can result in mass effect and compression of the tectal plate leading to obstructive hydrocephalus and Parinaud syndrome (upward gaze palsy).

See main article: intracranial germ cell tumours.

Leptomeningeal or intraventricular spread is not uncommon (occurring in 13% 2) at the time of diagnosis. Germinomas are receptive to radiation therapy and survival rates of ~85% are reported 3

See pineal region mass article. 


Pineal region masses

The pineal region is anatomically complex and plays host to a number of unique masses and tumours as well as potentially affected by many entities seen more frequently elsewhere in the brain. 

General reading

Pathology 

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Article Information

rID: 39248
Section: Pathology
Synonyms or Alternate Spellings:
  • Pineal germinomas

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