Plantar fibromatosis

Plantar fibromatosis, or Ledderhose disease, refers to a benign fibroblastic proliferation of the plantar fascia. It is classified as a type of musculoskeletal fibromatoses.

Plantar fibromatosis can be seen in both children and adults, although there is a recognised male predilection (M:F of 2:1).

Nodules or masses of plantar fibromatosis are typically located in the middle to the medial aspect of the plantar arch and may extend to involve the skin or deep structures of the foot. Lesions may be symptomatic because of a mass effect or invasion of adjacent muscles or neurovascular structures. In contrast to Dupuytren disease, flexion deformities usually do not occur 9.

Plantar fibromatosis is associated with other fibroproliferative disorders such as:

Unfortunately, exact aetiology of plantar fibromatosis is not well understood 4.

Often seen as a hypo to mixed echogenicity 3 discrete, fusiform, multi-nodular thickening of the plantar fascia located separately to the calcaneal insertion 1.

Again typically seen as a relatively well-defined region of multinodular thickening about the inferior margin of the plantar fascia.

  • T1: iso to low signal compared with muscle 1-2
  • T1 C+ (Gd): demonstrates variable contrast enhancement 4
  • T2: low to intermediate signal compared with muscle 1-2

Local excision with a wide margin is the treatment of choice for painful or disabling lesions.

Plantar fibromatosis is sometimes referred to as Ledderhose disease, Georg Ledderhose, German surgeon who first described it in 1894 7.​

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Article information

rID: 10808
Section: Pathology
Synonyms or Alternate Spellings:
  • Ledderhose disease
  • Ledderhose's disease

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