Pleural silicone granuloma

Last revised by Bruno Di Muzio on 2 Aug 2020

Pleural silicone granulomas result from an extremely rare situation where there is leakage of silicone from an implant rupture into the thorax. 


It is thought that scars from remote thoracotomy may provide a potential pathway for ruptured silicone to fistulise into the pleural space.

Radiographic features


Mild FDG uptake in these pleural lesions may be present and attributed to surrounding granulomatous inflammation.

Differential diagnosis

They may occasionally mimic intrapulmonary metastases 1.


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