Pleural synovial sarcoma
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At the time the article was created Yuranga Weerakkody had no recorded disclosures.View Yuranga Weerakkody's current disclosures
At the time the article was last revised Bruno Di Muzio had no recorded disclosures.View Bruno Di Muzio's current disclosures
Pleural synovial sarcoma is a rare tumor and refers to a primary synovial sarcoma arising from the pleura. It together with primary synovial sarcoma of the lung comes under the broader category of pleuro-pulmonary synovial sarcomas.
They are thought to comprise <1% of all primary lung malignancies 4. They typically occur in adolescents and young adults (between the ages of 15 and 40 years).
Their histological characteristics may be mistaken for those of malignant mesothelioma or other spindle cell tumors. Historically they are believed to originate from primitive pluripotent mesenchyme capable of synovial differentiation.
The presence of BCL-2 protein may be a helpful marker in distinguishing synovial sarcoma from mesothelioma.
Consider other pleural based tumors such as: