Pleural synovial sarcoma

Pleural synovial sarcoma is a rare tumour and refers to a primary synovial sarcoma arising from the pleura. It together with a primary synovial sarcoma of the lung comes under the broader category of pleuro-pulmonary synovial sarcomas.

They are thought to comprise <1% of all primary lung malignancies 4. They typically occur in adolescents and young adults (between the ages of 15 and 40 years)

Their histological characteristics may be mistaken for those of malignant mesothelioma or other spindle cell tumors. Historically they are believed to originate from primitive pluripotent mesenchyme capable of synovial differentiation.

The presence of bcl-2 protein may be a helpful marker in distinguishing synovial sarcoma from a mesothelioma

Consider other pleural based tumours such as

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Article information

rID: 40889
System: Chest
Synonyms or Alternate Spellings:
  • Pleural synovial sarcomas
  • Primary synovial sarcoma of pleura
  • Primary synovial sarcoma of the pleura

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Cases and figures

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    Figure 1: histology
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    Case 1
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