POEMS syndrome

POEMS syndrome is the acronymic name for a rare multisystem paraneoplastic disorder comprising of a minimum of three of the following features in the setting of a plasma cell dyscrasia:


POEMS occurs in the setting of plasma cell dyscrasias such as osteosclerotic myeloma or plasmacytoma. There is an overlap with multicentric Castleman disease 3.

See also

  • POEM procedure: unrelated procedure involving a esophageal myomectomy

Article information

rID: 8619
Section: Syndromes
Synonyms or Alternate Spellings:
  • Takatsuki disease
  • Crow–Fukase syndrome
  • PEP syndrome

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