The positive carpal sign is a useful radiographic sign for the diagnosis of Turner's syndrome in association with the other musculoskeletal manifestation.
Abnormality in the shape of the proximal carpal row in the dorsopalmar radiographs of the wrist and hand (taken in the neutral position is the key to the sign.
In order to obtain more precise data, two tangents lines must be drawn, the first touching the proximal contour of scaphoid and lunate bones and the second touching the triquetral and lunate bones. The intersection of these tangents resulted in an angle called the carpal angle.
When there is an abnormal angular shape of the proximal carpal row and the carpal angle is 117° or less; this is called the positive carpal sign 4.
- 1. Tauber M, Lounis N, Coulet J et-al. Wrist anomalies in Turner syndrome compared with Leri-Weill dyschondrosteosis: a new feature in Turner syndrome. Eur. J. Pediatr. 2004;163 (8): 475-81. Eur. J. Pediatr. (full text) - doi:10.1007/s00431-004-1471-4 - Pubmed citation
- 2. Bercu BB, Kramer SS, Bode HH. A useful radiologic sign for the diagnosis of Turner's syndrome. Pediatrics. 1976;58 (5): 737-9. Pediatrics (abstract) - Pubmed citation
- 3. Tiu CM, Liu TC, Hsieh CW et-al. Turner syndrome phalangeal screening based on a two-stage linear regression concept. Pediatr Int. 2009;51 (4): 453-9. Pediatr Int (full text) - doi:10.1111/j.1442-200X.2008.02797.x - Pubmed citation
- 4. Kosowicz J. The carpal sign in gonadal dysgenesis. J. Clin. Endocrinol. Metab. 1998;22: 949-52. Pubmed citation