Post lung volume reduction pulmonary edema

Last revised by Daniel J Bell on 23 Jan 2020

Post lung volume reduction pulmonary edema is a type of non cardiogenic pulmonary edema that can occur following lung volume reduction or a lung resection such as lobectomy or pneumonectomy.

It has been reported to occur in ~ 5% of right pneumonectomies,  ~4% of left pneumonectomies, and 1% of all lobectomies 2.

It tends to precipitate in the early postoperative period. Two pathophysiological factors have been proposed 1:

  • an increase in pulmonary capillary pressure associated with passage of a normal to high cardiac output in a reduced volume pulmonary vascular bed
  • injury to the alveolar capillary membrane

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