Posterior atrophy score of parietal atrophy

Last revised by Mark Thurston on 04 Jun 2017

The posterior atrophy score, a.k.a. Koedam score, has been developed to enable visual assessment of parietal atrophy on MRI, and is useful in the assessment of patients with possible dementia, especially atypical or early onset Alzheimer's disease (see: neurodegenerative MRI brain: an approach) 1,2

To generate this score, the brain must be viewed in three planes, and multiple structures assessed:

  1. sagittal plane
  2. coronal plane​​
  3. axial plane

The worse features are used to generate a grade of 0 to 3 1

  • grade 0: closed sulci, no gyral atrophy
  • grade 1: mild sulcal widening, mild gyral atrophy
  • grade 2: substantial sulcal widening, substantial gyral atrophy
  • grade 3: marked sulcal widening, knife-blade gyral atrophy

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