Posterior atrophy score of parietal atrophy

The posterior atrophy score, a.k.a. Koedam score, has been developed to enable visual assessment of parietal atrophy on MRI, and is useful in the assessment of patients with possible dementia, especially atypical or early onset Alzheimer's disease (see: neurodegenerative MRI brain: an approach) 1,2

To generate this score, the brain must be viewed in three planes, and multiple structures assessed:

  1. sagittal plane
  2. coronal plane​​
  3. axial plane

The worse features are used to generate a grade of 0 to 3 1

  • grade 0: closed sulci, no gyral atrophy
  • grade 1: mild sulcal widening, mild gyral atrophy
  • grade 2: substantial sulcal widening, substantial gyral atrophy
  • grade 3: marked sulcal widening, knife-blade gyral atrophy

Neurodegenerative diseases

Neurodegenerative diseases are legion and their classification just as protean. A useful approach is to divide them according to underlying pathological process, although even using this schema, there is much overlap and thus resulting confusion.

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Article Information

rID: 28450
Tags: refs, cases
Synonyms or Alternate Spellings:
  • Posterior atrophy score
  • PA score
  • Koedam score
  • Koedam score of parietal atrophy
  • Posterior cortical atrophy score
  • PCA score

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