Posterior atrophy score of parietal atrophy
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At the time the article was created Frank Gaillard had no recorded disclosures.
View Frank Gaillard's current disclosuresAt the time the article was last revised Mark Thurston had no recorded disclosures.
View Mark Thurston's current disclosures- Posterior atrophy score
- PA score
- Koedam score
- Koedam score of parietal atrophy
- Posterior cortical atrophy score
- PCA score
The posterior atrophy score, a.k.a. Koedam score, has been developed to enable visual assessment of parietal atrophy on MRI, and is useful in the assessment of patients with possible dementia, especially atypical or early onset Alzheimer's disease (see: neurodegenerative MRI brain: an approach) 1,2.
To generate this score, the brain must be viewed in three planes, and multiple structures assessed:
- sagittal plane
- coronal plane
- axial plane
The worse features are used to generate a grade of 0 to 3 1:
- grade 0: closed sulci, no gyral atrophy
- grade 1: mild sulcal widening, mild gyral atrophy
- grade 2: substantial sulcal widening, substantial gyral atrophy
- grade 3: marked sulcal widening, knife-blade gyral atrophy
References
- 1. Koedam EL, Lehmann M, van der Flier WM et-al. Visual assessment of posterior atrophy development of a MRI rating scale. Eur Radiol. 2011;21 (12): 2618-25. doi:10.1007/s00330-011-2205-4 - Free text at pubmed - Pubmed citation
- 2. Lehmann M, Koedam EL, Barnes J et-al. Posterior cerebral atrophy in the absence of medial temporal lobe atrophy in pathologically-confirmed Alzheimer's disease. Neurobiol. Aging. 2012;33 (3): 627.e1-627.e12. doi:10.1016/j.neurobiolaging.2011.04.003 - Free text at pubmed - Pubmed citation
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