Pregnancy of unknown location

Radswiki et al.

The term pregnancy of unknown location is assigned when neither intra nor extrauterine pregnancy is identified on transvaginal ultrasound (TVS) in the context of a positive pregnancy test.

  • pelvic pain, vaginal bleeding
  • positive pregnancy test
  • serial beta-hCG: has an adjunct role in the diagnosis of ectopic pregnancy, and is useful in folllow-up of clinically stable PUL.
  • serum progesterone: lack of progesterone has been considered an indication of nonviability 3
    • <5 ng/mL is a good indication of nonviability, however larger values cannot exclude an ectopic pregnancy 4
  1. very early pregnancy, not yet detected with ultrasound
  2. complete miscarriage
  3. unidentified ectopic pregnancy
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Article information

rID: 15322
System: Obstetrics
Synonyms or Alternate Spellings:
  • Pregnancy of unknown location (PUL)
  • Pregnancy of uncertain location (PUL)
  • PUL
  • Gestation of unknown location

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