Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Knipe H, Luong D, Premature thelarche. Reference article, Radiopaedia.org (Accessed on 10 Jun 2023) https://doi.org/10.53347/rID-72288
Disclosures:
At the time the article was last revised Henry Knipe had the following disclosures:
- Integral Diagnostics, Shareholder (ongoing)
- Micro-X Ltd, Shareholder (ongoing)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Henry Knipe's current disclosures
Premature thelarche is the onset of female breast development before age 7–8 years.
Pathology
As with age-appropriate thelarche, premature thelarche may be asymmetric or unilateral.
Premature thelarche may occur as an isolated event or as part of precocious puberty. Isolated premature thelarche generally occurs in girls aged 1-3 years and is non-progressive.
Radiographic features
Radiological evaluation for suspected precocious puberty should include a bone age assessment and abdominal and pelvic sonography to look for evidence of maturation of the uterus and ovaries. In addition, the ovaries and adrenal glands should be evaluated for estrogen-producing lesions, including:
Ultrasound
At sonography, premature thelarche appears as normal developing breast tissue without a discrete lesion.
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