Primary pulmonary enteric adenocarcinoma
Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Di Muzio B, Deng F, et al. Primary pulmonary enteric adenocarcinoma. Reference article, Radiopaedia.org (Accessed on 23 Jan 2025) https://doi.org/10.53347/rID-69272
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rID:
69272
Article created:
Disclosures:
At the time the article was created Yuranga Weerakkody had no recorded disclosures.
View Yuranga Weerakkody's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Bruno Di Muzio had no recorded disclosures.
View Bruno Di Muzio's current disclosures
Revisions:
4 times, by
4 contributors -
see full revision history and disclosures
Systems:
Sections:
Synonyms:
- Enteric adenocarcinoma of the lung
- Enteric adenocarcinoma of the lungs
- Pulmonary enteric adenocarcinoma
- Pulmonary enteric adenocarcinoma (PEAC)
- Pulmonary adenocarcinoma with enteric differentiation (PAED)
- Enteric adenocarcinoma of lung
- Enteric adenocarcinoma of lungs
- Primary pulmonary enteric adenocarcinomas
- Pulmonary adenocarcinoma with intestinal differentiation
- Pulmonary enteric adenocarcinoma
- Primary pulmonary enteric adenocarcinoma
Pulmonary enteric adenocarcinoma (PEAC) or pulmonary adenocarcinoma with enteric differentiation (PAED) is an extremely rare variant of primary invasive adenocarcinoma of the lung. It has morphological and immunohistochemical profiles overlapping with that of colorectal carcinoma. Due to this, it is difficult to diagnose and requires a definite exclusion of a colonic primary.
Terminology
It is usually defined as a primary pulmonary adenocarcinoma where the enteric component exceeds 50% and with an expression of at least 1 immunohistochemical marker of enteric differentiation.
References
- 1. Wang CX, Liu B, Wang YF, Zhang RS, Yu B, Lu ZF, Shi QL, Zhou XJ. Pulmonary enteric adenocarcinoma: a study of the clinicopathologic and molecular status of nine cases. (2014) International journal of clinical and experimental pathology. 7 (3): 1266-74. Pubmed
- 2. Li HC, Schmidt L, Greenson JK, Chang AC, Myers JL. Primary pulmonary adenocarcinoma with intestinal differentiation mimicking metastatic colorectal carcinoma: case report and review of literature. (2009) American journal of clinical pathology. 131 (1): 129-33. doi:10.1309/AJCPB04XWICTFERL - Pubmed
- 3. Hatanaka K, Tsuta K, Watanabe K, Sugino K, Uekusa T. Primary pulmonary adenocarcinoma with enteric differentiation resembling metastatic colorectal carcinoma: a report of the second case negative for cytokeratin 7. (2011) Pathology, research and practice. 207 (3): 188-91. doi:10.1016/j.prp.2010.07.005 - Pubmed
- 4. Nottegar A, Tabbò F, Luchini C, Brunelli M, Bria E, Veronese N, Santo A, Cingarlini S, Gilioli E, Ogliosi C, Eccher A, Montagna L, Pedron S, Doglioni C, Cangi MG, Inghirami G, Chilosi M. Pulmonary Adenocarcinoma With Enteric Differentiation: Immunohistochemistry and Molecular Morphology. (2018) Applied immunohistochemistry & molecular morphology : AIMM. 26 (6): 383-387. doi:10.1097/PAI.0000000000000440 - Pubmed
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