Primary pulmonary enteric adenocarcinoma

Pulmonary enteric adenocarcinoma (PEAC) or pulmonary adenocarcinoma with enteric differentiation (PAED) is an extremely rare variant of primary invasive adenocarcinoma of the lung. It has morphological and immunohistochemical profiles overlapping with that of colorectal carcinoma. Due to this it is is difficult to diagnose and requires definite exclusion of a colonic primary.


It is usually defined as a primary pulmonary adenocarcinoma where the enteric component exceeds 50% and with expression of at least 1 immunohistochemical marker of enteric differentiation.

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Article information

rID: 69272
System: Chest
Section: Pathology
Synonyms or Alternate Spellings:
  • Pulmonary enteric adenocarcinoma
  • Pulmonary adenocarcinoma with intestinal differentiation
  • Primary pulmonary enteric adenocarcinomas
  • Primary pulmonary enteric adenocarcinoma
  • Enteric adenocarcinoma of lungs
  • Enteric adenocarcinoma of lung
  • Pulmonary adenocarcinoma with enteric differentiation (PAED)
  • Pulmonary enteric adenocarcinoma (PEAC)
  • Pulmonary enteric adenocarcinoma
  • Enteric adenocarcinoma of the lungs
  • Enteric adenocarcinoma of the lung

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