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Citation:
Weerakkody Y, Tatco V, Jha P, Primary serous papillary carcinoma of the peritoneum. Reference article, Radiopaedia.org (Accessed on 19 Apr 2024) https://doi.org/10.53347/rID-13591
A primary serous papillary carcinoma of the peritoneum (PSPCP) is an extremely rare primary peritoneal tumor.
They usually present in postmenopausal women.
Patients tend to present with non-specific complaints such as abdominal pain, anorexia, and abdominal distention.
It is histologically identical to serous papillary carcinoma of the ovary 7. PSPCP is believed to originate from either peritoneal mesothelial cells with müllerian differentiation or nests of ovarian tissue remnants within the peritoneum
Markers
Serum CA-125 levels may be elevated 3-4.
CT
While most features are nonspecific, CT features of diffuse peritoneal, omental and mesenterial involvement especially in middle-aged or elderly postmenopausal women with normal-size ovaries in the absence of an identifiable primary site in and conjunction with elevated level of serum CA-125 may suggest the possibility of PSPCP 6.
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On imaging, a PSPCP can resemble that of peritoneal carcinomatosis
Other considerations include
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7. Kebapci M, Yalcin OT, Dündar E et-al. Computed tomography findings of primary serous papillary carcinoma of the peritoneum in women. Eur. J. Gynaecol. Oncol. 2003;24 (6): 552-6. - Pubmed citation
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