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Prostate sarcomas are an uncommon and heterogeneous group of tumors arising from mesenchymal cells in and around the prostate (as opposed to the more common prostate adenocarcinoma which derives from the glandular tissue).
In children, the most common tumor type is a prostatic rhabdomyosarcoma, which accounts for approximately a third of all prostatic sarcomas 1.
In adults, leiomyosarcomas are most common, accounting for approximately a quarter of all cases 1. Many other sarcomas have been reported although in general they are rare.
Overall, prostatic sarcomas include 1,2:
- rhabdomyosarcoma of the prostate: most common in children
- leiomyosarcoma of the prostate: most common in adults
- sarcomatoid carcinoma of the prostate
- malignant fibrous histiocytoma of the prostate
- phyllodes tumor (also known as cystosarcoma phyllodes of the prostate)
- undifferentiated stromal sarcoma of the prostate
- 1. Bland KI, Daly JM, Karakousis CP. Surgical oncology, contemporary principles & practice. McGraw-Hill Professional. (2001) ISBN:0838587364. Read it at Google Books - Find it at Amazon
- 2. Bostwick DG, Cheng L. Urologic surgical pathology. Mosby Inc. (2008) ISBN:0323019706. Read it at Google Books - Find it at Amazon