Prostatic cystadenoma

Last revised by Dr Jeremy Jones on 20 Sep 2021

Prostatic cystadenoma or multilocular cystadenoma of prostate is a rare benign neoplasm arising in the prostate gland.

If lesions are considerably large they may also be termed giant multilocular cystadenomas of the prostate.

Lesions are histologically characterized by glands and cysts lined with cuboidal epithelium in a hypocellular fibrous stroma. Positive immunohistochemical staining of epithelial cells for PSA often confirm their prostatic origins. Macroscopically, the lesions are generally well circumscribed.

May show a large multiseptated cystic mass +/- some soft-tissue components may be present.

The natural history of prostatic cystadenomas are not well known, and there may be varying opinions on optimum management strategies. Although they are benign lesions, cystadenomas can be locally aggressive and be adherent to surrounding viscera.

Imaging differential considerations include:

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