Pseudo-TORCH syndrome

Pseudo-TORCH syndrome is a term used to denote cases that clinically resemble congenital infection (see congenital TORCH infections) but where no organisms or serological, microbiological or immunological evidence of infection can be identified ¹. It is now believed that pseudo-TORCH syndrome is actually Aicardi-Goutières syndrome ².  

Radiographic features

• basal ganglia calcifications
• periventricular calcifications
• progressive demyelination in cerebrum and cerebellum

CSF STUDY :-

• Pleocytosis
• Increase CSF alpha interferon