Pseudocirrhosis is a complication of treated hepatic metastases, mainly those of breast cancer, which mimics liver cirrhosis radiologically. It has been reported in up to 50% of patients with breast cancer and liver metastases who underwent chemotherapy treatment 1. It is seen in the next weeks or months following treatment.
There is some controversy regarding whether or not the term pseudocirrhosis is a misnomer, since patients may develop portal hypertension.
Radiological manifestations on CT scan, ultrasound and liver MRI are the same as usual liver cirrhosis, and consist mainly of:
- hepatic segmental volume loss
- caudate lobe enlargement
- capsular retraction
- 1. Lee SL, Chang ED, Na SJ et-al. Pseudocirrhosis of breast cancer metastases to the liver treated by chemotherapy. Cancer Res Treat. 2014;46 (1): 98-103. doi:10.4143/crt.2014.46.1.98 - Free text at pubmed - Pubmed citation
- 2. Jeong WK, Choi SY, Kim J. Pseudocirrhosis as a complication after chemotherapy for hepatic metastasis from breast cancer. Clin Mol Hepatol. 2013;19 (2): 190-4. doi:10.3350/cmh.2013.19.2.190 - Free text at pubmed - Pubmed citation
- 3. Jha P, Poder L, Wang ZJ et-al. Radiologic mimics of cirrhosis. AJR Am J Roentgenol. 2010;194 (4): 993-9. doi:10.2214/AJR.09.3409 - Pubmed citation