Pseudocirrhosis

Changed by Matt A. Morgan, 21 Jan 2015

Updates to Article Attributes

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Pseudocirrhosis is a complication of treated hepatic metastases, mainly those of  breast cancer, which mimics liver cirrhosis radiologically. It has been reported in up to 50% of patients with breast cancer and liver metastases who underwent chemotherapy treatment 31. It is seen in the next weeks or months following treatment.

There is some controversy regarding whether or not the term pseudocirrhosis is a misnomer, since patients may develop portal hypertension.

Radiographic features

Radiological manifestations on CT-scan scan, ultrasound and liver MRI are the same as usual liver cirrhosis, and consist mainly of:

  • hepatic segmental volume loss
  • caudate lobe enlargement
  • capsular retraction
  • -<p><strong>Pseudocirrhosis</strong> is a complication of treated hepatic metastases, mainly those of  breast cancer, which mimics <a href="/articles/cirrhosis">liver cirrhosis</a> radiologically. It has been reported in up to 50% of patients with breast cancer and liver metastases who underwent chemotherapy treatment <sup>3</sup>. It is seen in the next weeks or months following treatment.</p><p>There is some controversy regarding whether or not the term pseudocirrhosis is a misnomer, since patients may develop portal hypertension.</p><h4>Radiographic features</h4><p>Radiological manifestations on CT-scan, ultrasound and liver MRI are the same as usual liver cirrhosis, and consist mainly of:</p><ul>
  • +<p><strong>Pseudocirrhosis</strong> is a complication of treated hepatic metastases, mainly those of  breast cancer, which mimics <a href="/articles/cirrhosis">liver cirrhosis</a> radiologically. It has been reported in up to 50% of patients with breast cancer and liver metastases who underwent chemotherapy treatment <sup>1</sup>. It is seen in the next weeks or months following treatment.</p><p>There is some controversy regarding whether or not the term pseudocirrhosis is a misnomer, since patients may develop portal hypertension.</p><h4>Radiographic features</h4><p>Radiological manifestations on CT scan, ultrasound and liver MRI are the same as usual liver cirrhosis, and consist mainly of:</p><ul>

References changed:

  • 3. Jha P, Poder L, Wang ZJ et-al. Radiologic mimics of cirrhosis. AJR Am J Roentgenol. 2010;194 (4): 993-9. <a href="http://dx.doi.org/10.2214/AJR.09.3409">doi:10.2214/AJR.09.3409</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/20308502">Pubmed citation</a><div class="ref_v2"></div>
  • 3. Lee SL, Chang ED, Na SJ et-al. Pseudocirrhosis of breast cancer metastases to the liver treated by chemotherapy. Cancer Res Treat. 2014;46 (1): 98-103. <a href="http://dx.doi.org/10.4143/crt.2014.46.1.98">doi:10.4143/crt.2014.46.1.98</a> - <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918533">Free text at pubmed</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/24520229">Pubmed citation</a><div class="ref_v2"></div>
  • 4. Jeong WK, Choi SY, Kim J. Pseudocirrhosis as a complication after chemotherapy for hepatic metastasis from breast cancer. Clin Mol Hepatol. 2013;19 (2): 190-4. <a href="http://dx.doi.org/10.3350/cmh.2013.19.2.190">doi:10.3350/cmh.2013.19.2.190</a> - <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701853">Free text at pubmed</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/23837145">Pubmed citation</a><div class="ref_v2"></div>
  • 5. Jha P, Poder L, Wang ZJ et-al. Radiologic mimics of cirrhosis. AJR Am J Roentgenol. 2010;194 (4): 993-9. <a href="http://dx.doi.org/10.2214/AJR.09.3409">doi:10.2214/AJR.09.3409</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/20308502">Pubmed citation</a><div class="ref_v2"></div>

Tags changed:

  • chemotherapy
  • liver
Images Changes:

Image 1 CT (liver window) ( create )

Caption was added:
Case 1: pseudocirrhosis

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