Pseudolipoma of the Glisson capsule
Pseudolipoma of the Glisson capsule is an uncommon developmental anomaly in which a piece of colonic epiploic fat becomes ectopically located within the liver capsule.
Radiographic features
CT
- well-circumscribed fat attenuation (-20 to -70 HU) nodule at the liver surface
- it can sometimes have soft tissue attenuation and can have a small peripheral calcification 3
MRI
- well-circumscribed nodule at the liver surface that follows fat signal intensity on all sequences and suppresses with fat saturation
Differential diagnosis
They might be mistaken by peripheral intra-hepatic fat-containing lesions and, therefore, the differential diagnosis would include:
- hepatic lipoma
- hepatic adenoma
- focal hepatic steatosis
- hepatocellular carcinoma
- metastases from lipid-containing tumors like a liposarcoma
- lipopeliosis
- pseudocyst of the Glisson capsule
Other differentials considerations include:
Related Radiopaedia articles
Hepatobiliary pathology
- depositional disorders
- infection and inflammation
- liver abscess
- hepatic hydatid infection
- cirrhosis
- hepatitis
- cholecystitis
- cholangitis
- malignancy
- liver and intrahepatic bile duct tumors
- benign epithelial tumors
- hepatocellular hyperplasia
- hepatocellular adenoma
- hepatic/biliary cysts
- benign nonepithelial tumors
- primary malignant epithelial tumors
- hepatocellular carcinoma
- hepatocellular carcinoma variants
-
cholangiocarcinoma
- intra-hepatic
- mass-forming type
- periductal infiltrating type - Klatskin tumors
- intraductal growing type
- extra-hepatic/large duct type
- intra-hepatic
- biliary cystadenocarcinoma
- combined hepatocellular and cholangiocarcinoma
- hepatoblastoma
- undifferentiated carcinoma
- primary malignant nonepithelial tumors
- hematopoietic and lymphoid tumors
- primary hepatic lymphoma
- hepatic myeloid sarcoma (hepatic chloroma)
- secondary tumors
- miscellaneous
- adrenal rest tumors
- hepatic carcinosarcoma
- hepatic fibroma
- hepatic Kaposi sarcoma
- hepatic lipoma
- hepatic mesenchymal hamartoma
- hepatic myxoma
- hepatic rhabdoid tumor
- hepatic solitary fibrous tumor
- hepatic teratoma
- hepatic yolk sac tumor
- inflammatory myofibroblastic tumor (inflammatory pseudotumor)
- nodular regenerative hyperplasia
- pancreatic rest tumors
- primary hepatic carcinoid
- benign epithelial tumors
- liver and intrahepatic bile duct tumors
- metabolic
- trauma
-
vascular and perfusion disorders
- portal vein related
- hepatic artery related
- hepatic veins related
- inferior vena cava related
- other
- third inflow
- liver thrombotic angiitis
- infra diaphragmatic total anomalous pulmonary venous return (TAPVR)
- hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease)
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