Puff of smoke sign

Last revised by Francis Deng on 25 Nov 2023

The puff of smoke sign describes the characteristic angiographic appearance of tiny abnormal intracranial collateral vessel networks in moyamoya disease. Progressive narrowing of the supraclinoid internal carotid arteries and circle of Willis vessels results in extensive small collateral arterial networks evolving from the lenticulostriate and choroidal arteries. When viewed angiographically, the abnormal collaterals simulate smoke emanating away from the major supplying artery.

Video

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.