Pulmonary leukaemic infiltratation

Pulmonary leukaemic infiltration is a complication that can occur in forms of leukaemia.

They can be found in the lungs in around 24-64% of patients with leukaemia on autopsy.

Pathologically there is atypical lymphocyte infiltration along the interstitium and the alveolar spaces.

It can have a variety of radiographic radiographic appearances.

Chest radiograph

Most infiltrates do not appear on chest radiographs 1.

HRCT - chest CT

A variety of pattern have been described include pulmonary infiltrates with alveolar, interstitial, mixed and peribronchial/perivascular patterns 3.  There is a general tendency for abnormalities to involve the perilymphatic interstitium 1.

Other reported findings include 1,4

Due to variable patterns, the differential on CT can be broad and can include 1

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Article Information

rID: 26725
System: Chest
Tags: stub, cases, refs
Synonyms or Alternate Spellings:
  • Pulmonary leukaemic infiltratates
  • Leukaemic pulmonary infiltration
  • Leukaemic pulmonary infiltrates
  • Leukaemic infiltration of the lung
  • Pulmonary leukemic infiltratation
  • Leukemic pulmonary infiltration
  • Leukemic pulmonary infiltrates

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