Pulmonary necrotising granuloma

Pulmonary necrotising granuloma refers to rather blanket term covering a group of entities which can result in granuloma formation with associated necrosis. 

Pathology

On a pathologic specimen a necrotizing granuloma comprises of aggregates of macrophages transformed into epithelium-like cells surrounded by a collar of mononuclear leukocytes (principally lymphocytes and occasional plasma cells) with a surrounding area of necrosis.

They can result from both infectious and non infectious causes.

According to a recent study, most of these were caused by unexplained aetiology 1. Of the known aetiologies, infectious causes tend to be more commoner.

The pathological spectrum includes

See also

Share article

Article information

rID: 28462
System: Chest
Synonyms or Alternate Spellings:
  • Pulmonary necrotising granulomas
  • Pulmonary necrotising granulomata
  • Pulmonary necrotizing granuloma
  • Pulmonary necrotizing granulomas
  • Necrotising granuloma of lung
  • Necrotising granuloma of lungs
  • Necrotising granuloma of the lungs

Support Radiopaedia and see fewer ads

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.