Pulmonary necrotizing granuloma

Pulmonary necrotizing granuloma refers to rather blanket term covering a group of entities which can result in granuloma formation with associated necrosis. 


On a pathologic specimen a necrotizing granuloma comprises of aggregates of macrophages transformed into epithelium-like cells surrounded by a collar of mononuclear leukocytes (principally lymphocytes and occasional plasma cells) with a surrounding area of necrosis.

They can result from both infectious and non infectious causes.

According to a recent study, most of these were caused by unexplained etiology 1. Of the known etiologies, infectious causes tend to be more commoner.

The pathological spectrum includes

See also

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Article information

rID: 28462
System: Chest
Synonyms or Alternate Spellings:
  • Pulmonary necrotising granulomas
  • Pulmonary necrotising granulomata
  • Pulmonary necrotizing granuloma
  • Pulmonary necrotizing granulomas
  • Necrotising granuloma of lung
  • Necrotising granuloma of lungs
  • Necrotising granuloma of the lungs

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