Pulmonary non-tuberculous mycobacterial infection
Updates to Article Attributes
Body
was changed:
Pulmonary non-tuberculous mycobacterial (NTM) infection refers to pulmonary infection caused by one of the large number (at least 150) mycobacterial species other than Mycobacterium tuberculosis. However, certain species are much more common than others.
Pathology
As with M. tuberculosis NTMs commonly cause pulmonary infection.
These organisms include:
- Mycobacterium avium-intracellulare: ~60% (on bronchial secretions)
- Mycobacterium kansasii: ~25%
- Mycobacterium fortuitum
- Mycobacteriumgordonae
- Mycobacterium szulgai
- Mycobacterium scrofulaceum / Mycobacterium parascrofulaceum
- Mycobacterium xenopi
- Mycobacterium chelonae: pulmonary mycobacterium chelonae infection
- Mycobacterium simiae
- Mycobacterium abscesssus: pulmonary mycobacterium abscessus infection 2
Risk factors
The organisms have a prediction for individuals with pre-existing chronic obstructive pulmonary disease, with debilitating illnesses or various forms of immunocompromise.
Associations
There may be an association achalasia of gastric cardia and M. fortuitum/chelonae infection.
Treatment and prognosis
The guideline on the management approach can be found in reference 12.
-</ul><h5>Risk factors</h5><p>The organisms have a prediction for individuals with pre-existing <a href="/articles/chronic-obstructive-pulmonary-disease-1">chronic obstructive pulmonary disease</a>, with debilitating illnesses or various forms of immunocompromise.</p><h5>Associations</h5><p>There may be an association achalasia of gastric cardia and <em>M. fortuitum</em>/<em>chelonae </em>infection.</p>- +</ul><h5>Risk factors</h5><p>The organisms have a prediction for individuals with pre-existing <a href="/articles/chronic-obstructive-pulmonary-disease-1">chronic obstructive pulmonary disease</a>, with debilitating illnesses or various forms of immunocompromise.</p><h5>Associations</h5><p>There may be an association achalasia of gastric cardia and <em>M. fortuitum</em>/<em>chelonae </em>infection.</p><h4>Treatment and prognosis</h4><p>The guideline on the management approach can be found in reference 12.</p>
References changed:
- 12. Haworth C, Banks J, Capstick T et al. British Thoracic Society Guideline for the Management of Non-Tuberculous Mycobacterial Pulmonary Disease (NTM-PD). BMJ Open Respir Res. 2017;4(1):e000242. <a href="https://doi.org/10.1136/bmjresp-2017-000242">doi:10.1136/bmjresp-2017-000242</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/29449949">Pubmed</a>