Pulmonary scedoporidium infection
Pulmonary scedoporidium infection is a form of extremely rare pulmonary fungal infection. Scedosporium can present as focal localised to widespread systemic disease.
It typically occurs in immunucompromised patients. Both acute and chronic forms have been described.
This occurs due to infection with several species such as
- Scedoporidium prolificans
- Scedoporidium angiospermum
It may give a clinical presentation similar to that of pulmonary aspergillosis.
There are currently very little publications on the imaging features at the time of initial writing. If youre are an expert on this we would love your help :).
Treatment and prognosis
Scedosporium infections in transplant recipients have been reported to have high rates of dissemination and a poor overall outcome. It is usually resistant to traditional antifungal agents, and may respond to prompt management with triazoles (variconazole).
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- 2. Koga T, Kitajima T, Tanaka R et-al. Chronic pulmonary scedosporiosis simulating aspergillosis. Respirology. 2005;10 (5): 682-4. doi:10.1111/j.1440-1843.2005.00769.x - Pubmed citation
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- 4. Husain S, Muñoz P, Forrest G et-al. Infections due to Scedosporium apiospermum and Scedosporium prolificans in transplant recipients: clinical characteristics and impact of antifungal agent therapy on outcome. Clin. Infect. Dis. 2005;40 (1): 89-99. doi:10.1086/426445 - Pubmed citation
- 5. Sarva ST, Manjunath SK, Baldwin HS et-al. Lung scedosporiosis in human immunodeficiency virus/acquired immunodeficiency syndrome. Am. J. Med. Sci. 2010;339 (3): 300-3. doi:10.1097/MAJ.0b013e3181cec4be - Pubmed citation