Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Bell D, Pulmonary mycobacterium parascrofulaceum infection. Reference article, Radiopaedia.org (Accessed on 28 Nov 2023) https://doi.org/10.53347/rID-99951
Pulmonary mycobacterium parascrofulaceum infection results from infection by the species Mycobacterium parascrofulaceum, which is a relatively new species of non-tuberculous mycobacterium (NTM) belonging to group 2. Infection by this species is rare and infrequently reported and the lung is considered the most common organ involved.
Mycobacterium parascrofulaceum phenotypically resembles M. simiae although its closest genotypic relative is M. scrofulaceum.
CT
Mycobacterium parascrofulaceum infection can be variable difficult to differentiate from other non-tuberculous mycobacterial infections. Some reported features include bronchiectasis with peribronchial infiltration and centrilobular nodules.
Treatment and prognosis
Mycobacterium parascrofulaceum has been reported to be susceptible to clarithromycin, rifampin and levofloxacin 5.
History and etymology
It was first reported in 2004 by Turenne et al. 3.
- 1. Tortoli E, Chianura L, Fabbro L et al. Infections Due to the Newly Described Species Mycobacterium Parascrofulaceum. J Clin Microbiol. 2005;43(8):4286-7. doi:10.1128/jcm.43.8.4286-4287.2005 - Pubmed
- 2. Jae Seok Park, Wonmok Lee, Young June Jeon. Nontuberculous Mycobacterial Lung Disease Caused by Mycobacterium Parascrofulaceum in an Immunocompetent Patient. Eur Respir J. 2014;44 (Suppl 58).
- 3. Ikegami H, Yamasaki K, Kawanami T et al. Pulmonary Mycobacterium Parascrofulaceum Infection in a Patient with Chronic Progressive Pulmonary Aspergillosis: A Case Report and Literature Review. Intern Med. 2020;59(11):1417-22. doi:10.2169/internalmedicine.3540-19 - Pubmed
- 4. Turenne C, Cook V, Burdz T et al. Mycobacterium Parascrofulaceum Sp. Nov., Novel Slowly Growing, Scotochromogenic Clinical Isolates Related to Mycobacterium Simiae. Int J Syst Evol Microbiol. 2004;54(Pt 5):1543-51. doi:10.1099/ijs.0.02940-0 - Pubmed
- 5. Teruya H, Tateyama M, Hibiya K et al. Pulmonary Mycobacterium Parascrofulaceum Infection as an Immune Reconstitution Inflammatory Syndrome in an AIDS Patient. Intern Med. 2010;49(16):1817-21. doi:10.2169/internalmedicine.49.3616 - Pubmed
- 6. Liu G, Wang G, Yu X et al. Bacteriological Characterization of a Mycobacterium Parascrofulaceum Strain Isolated from a Chinese Pneumonia Patient. Int J Infect Dis. 2014;25:82-7. doi:10.1016/j.ijid.2014.01.023 - Pubmed
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