Pure ground glass lung nodules are a subtype of ground glass lung nodules where there is no associated solid component.
They have been shown to represent various pathologies such as 1,3
- adenocarcinoma in situ of lung
- minimally-invasive adenocarcinoma of lung
- invasive adenocarcinoma of lung
- atypical adenomatous hyperplasia of lung
- focal interstitial fibrosis
According to one study, conducted in nodules measuring between 3-20 mm over a two-year period without a history of malignancy, 90% did not grow on follow up 2.
Follow up recommendations
- 1. Lim HJ, Ahn S, Lee KS et-al. Persistent pure ground-glass opacity lung nodules ≥ 10 mm in diameter at CT scan: histopathologic comparisons and prognostic implications. Chest. 2013;144 (4): 1291-9. doi:10.1378/chest.12-2987 - Pubmed citation
- 2. Chang B, Hwang JH, Choi YH et-al. Natural history of pure ground-glass opacity lung nodules detected by low-dose CT scan. Chest. 2013;143 (1): 172-8. doi:10.1378/chest.11-2501 - Pubmed citation
- 3. Kim TJ, Goo JM, Lee KW et-al. Clinical, pathological and thin-section CT features of persistent multiple ground-glass opacity nodules: comparison with solitary ground-glass opacity nodule. Lung Cancer. 2009;64 (2): 171-8. doi:10.1016/j.lungcan.2008.08.002 - Pubmed citation