Putaminal rim sign

Last revised by Assoc Prof Frank Gaillard on 15 Oct 2021

The putaminal rim sign, also known as the putaminal slit sign, is said to be a relatively specific sign of multiple system atrophy - parkinsonism (MSA-P), and refers to a linear region of high signal surrounding the lateral aspect of the putamen at 1.5 T MRI on T2 weighted images or ADC map.

Unfortunately, this appearance can be seen in normal individuals when imaged with 3T MRI 1

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