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Radiation-induced neuritis

Dr Bruno Di Muzio and Dr Maxime St-Amant et al.

Radiation-induced neuritis is a complication of radiotherapy that may present with visible changes on MRI. It is likely to be most relevant in the head and neck region. There is only scarce radiology literature on the subject and radiation-induced optic neuritis is best documented.

Radiographic features


Radiation-induced neuritis may demonstrate thickening of the affected nerves with and T2 hyperintense signal and enhancement 1.

  • T2: hyperintense perineural signal
  • T1C+ (Gd): perineural enhancement

Differential diagnosis

The main differential diagnosis is perineural spread of tumor. However, the latter usually demonstrates more nodular enhancement and is usually FDG avid on PET-scan. If accessible, biopsy of the affected site may provide a definitive answer.

Radiation therapy

Article information

rID: 60805
Synonyms or Alternate Spellings:
  • Radiation-induced neuropathy
  • Radiation neuropathy
  • Radiation neuritis

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