Radionuclide cisternography

Dr Henry Knipe and Dr Francis Deng et al.

Radionuclide cisternography is a nuclear medicine imaging technique that uses intrathecal 111In-DTPA (diethyletriaminepentaacetic acid; pentetate) to visualize the flow of cerebrospinal fluid (CSF).

There are few indications 1:

Imaging occurs at 2-6 hours after injection into the lumbar subarachnoid space and then delayed imaging is performed at 18-24 hours, sometimes even with additional images at 72 hours.

These days, the test is uncommonly performed. For evaluation of normal pressure hydrocephalus, the cisternographic pattern is not predictive of response to surgical shunting 2. For CSF leak identification, CT is usually adequate for identifying a defect 3.

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Article information

rID: 67325
Section: Radiography
Synonyms or Alternate Spellings:
  • Isotope cisternography
  • Isotope cisternogram
  • Radionuclide cisternogram

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Cases and figures

  • Case 1: post-operative spinal CSF leak
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