Ranson criteria

Last revised by Dr Daniel J Bell on 07 Aug 2019

Ranson criteria are useful in assessing prognosis in early acute pancreatitis. The more of the criteria are met the higher the mortality. Ranson criteria are assessed both at admission and at 48 hours.

Criteria

On admission
  • age: >55 years
  • white blood count: >16 000/mL
  • blood glucose level: >11.0 mmol/L
  • lactate dehydrogenase (LDH): >350 IU/L
  • aspartate aminotransferase (AST): >250 U/L
At 48 hours
  • packed cell volume: decrease >10% from admission
  • urea: increase >1.8 mmol/L from admission
    • equivalent to blood urea nitrogen (BUN): increase >5 mg/dL from admission
  • calcium: <2 mmol/L
  • oxygen partial pressure: <60 mmHg
  • base deficit: >4 mmol/L
  • fluid sequestration: >6 L

Prognosis

  • 0-2 criteria: <1% mortality
  • 3-4 criteria: 16% mortality
  • 5 or more: >40% mortality

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