Recurrent spontaneous hypothermia with hyperhidrosis syndrome
The recurrent spontaneous hypothermia with hyperhidrosis syndrome is a rare syndrome characterised by:
The findings are thought secondary to hypothalamic dysfunction with associated water balance abnormalities.
A "reverse Shapiro's syndrome" has also been described, where patients have hyperthermia.
- 3. Hirayama K. "Reverse Shapiro's syndrome. A case of agenesis of corpus callosum associated with periodic hyperthermia" Neurology 2007;69:1293-1297
- 1. Albon LM "Hypothalamic dysfunction in Shapiro's syndrome may cause abnormalities of thirst and appetite perception" Endocrine Abstracts (2002) 4 P24
- 2. W. R. Shapiro, G.H. Williams and F. Plum Brain, 1969, 92:2,423-36